Research Reveals Existence of More Transmissible, Damaging Variant of HIV
People living with the newly revealed HIV subtype experience double the rate of immune system decline (CD4 count), have higher HIV viral loads (amount of virus in the blood) and are vulnerable to developing AIDS two to three times faster after diagnosis than if they were living with other strains of the virus.
The study, led by researchers from the University of Oxford’s Big Data Institute, was the first to discover this highly virulent variant of the subtype-B of HIV.
The study also revealed that the variant has been circulating in the Netherlands for years and remains receptive to HIV treatment.
The HIV pandemic continues to take a life every minute and scientists have long worried about the evolution of new, more transmissible, variants of HIV.
This newly identified variant does not represent a major public health threat but underscores the urgency of speeding up efforts to halt the HIV pandemic.
"Ten million people living with HIV worldwide are not yet on treatment, fuelling the continued spread of the virus and potential for further variants," said Eamonn Murphy, UNAIDS Programme Deputy Executive Director, in a press release on Monday.
"We urgently need to deploy cutting-edge medical innovations in ways that reach the communities most in need. Whether it’s HIV treatment or COVID-19 vaccines, inequalities in access are perpetuating pandemics in ways that harm us all," Murphy added.
HIV remains the deadliest pandemic of our time—an estimated 79 million people have become infected with the virus, for which there is still no vaccine and no cure.
Some 36 million people have died from AIDS-related illnesses since the start of the pandemic and 1.5 million people were newly infected with HIV in 2020.
Of the 38 million people living with HIV today, 28 million are on life-saving antiretroviral therapy, keeping them alive and well and preventing transmission of the virus.
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